The Accra Fast Track High Court, presided over by Mr Justice Mohammed Habib Logoh, Tuesday remanded into custody the two Nigerians who were picked up for allegedly importing into the country 200 kilogrammes of cocaine.
The alleged owner of the drug, Chief Sunny Ekechukwu Benji Eke, a 53-year-old Nigerian businessman, was remanded together with an alleged accomplice, James Elekechukwu, 47, a second-hand clothes dealer in Accra.
They are to reappear on March 12, 2013.
The two have been charged with two counts of engaging in criminal conspiracy and importation of a narcotic drug, while Elekechukwu faces an additional charge of possession of a narcotic drug.
Their pleas were not taken.
The seizure of the drug, said to have a street value of $12 million, has been described as the largest in recent years at the Tema Harbour.
It was concealed in a 40-footer container filled with 1,946 boxes of shampoo imported from Bolivia in South America.